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Orvepitant maleate

Product Specifications

CAS Number

579475-24-4

Target

Neurokinin receptor

Related Pathways

Neuroscience|||GPCR/G Protein

Bioactivity

Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor) . Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment. Orvepitant maleate can across the blood-brain barrier.

Smiles

OC(=O)\C=C/C(O)=O.[H][C@@]12CCC(=O)N1CCN(C2)[C@H]1CCN([C@H](C1)c1ccc(F)cc1C)C(=O)N(C)[C@H](C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

Molecular Formula

C35H39F7N4O6

Molecular Weight

744.7

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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