OP-3633
Product Specifications
Target
Others|||Glucocorticoid Receptor
Related Pathways
Endocrinology/Hormones|||Others
Bioactivity
OP-3633 is an effective and selective steroidal glucocorticoid receptor (GR) antagonist (IC50: 29 nM) . OP-3633 shows low progesterone receptor (PR) agonism and androgen receptor (AR) antagonism. It also has an inhibition of GR transcriptional activity.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@]3(C5=CC=C(N(C)C)C=C5)[H])[C@@](C#CC)(O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]
Molecular Formula
C30H39NO2
Molecular Weight
445.64
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/8666E806-DC22-47C4-B881-51F412169861/T16396
CAS Number
2102494-14-2
Available Sizes
Curated Selection
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