Omapatrilat
Product Specifications
CAS Number
167305-00-2
Target
Neprilysin, RAAS
Related Pathways
Endocrinology/Hormones, Metabolism
Purity
0.9887
Bioactivity
Omapatrilat is an orally active dual inhibitor of ACE (angiotensin-converting enzyme) and NEP (neprilysin), with Ki values of 0.64 and 0.45 nM, respectively, capable of suppressing induced hypotension in rats.
Smiles
C(O)(=O)[C@H]1N2[C@](CCC1)(SCC[C@H](NC([C@H](CC3=CC=CC=C3)S)=O)C2=O)[H]
Molecular Formula
C19H24N2O4S2
Molecular Weight
408.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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