Olutasidenib
Product Specifications
CAS Number
1887014-12-1
Target
Isocitrate Dehydrogenase (IDH), Dehydrogenase
Related Pathways
Metabolism
Purity
0.9959
Bioactivity
Olutasidenib (FT-2102) is under the study in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) . Olutasidenib is a highly effective, brain penetrant, and selective inhibitor of the mutant Isocitrate dehydrogenase 1 (IDH1) (IC50: 21.2 nM and 114 nM for IDH1- R132H and IDH1- R132C, respectively) .
Smiles
C[C@H](Nc1ccc(C#N)n(C)c1=O)c1cc2cc(Cl)ccc2[nH]c1=O
Molecular Formula
C18H15ClN4O2
Molecular Weight
354.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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