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Oglemilast

Product Specifications

CAS Number

778576-62-8

Target

PDE

Related Pathways

Metabolism

Purity

0.9982

Bioactivity

Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM for PDE4D3) . Oglemilast has the potential for inflammatory airway diseases.

Smiles

CS(=O)(=O)Nc1ccc2oc3c(OC(F)F)ccc(C(=O)Nc4c(Cl)cncc4Cl)c3c2c1

Molecular Formula

C20H13Cl2F2N3O5S

Molecular Weight

516.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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