Oglemilast
Product Specifications
CAS Number
778576-62-8
Target
PDE
Related Pathways
Metabolism
Purity
0.9982
Bioactivity
Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM for PDE4D3) . Oglemilast has the potential for inflammatory airway diseases.
Smiles
CS(=O)(=O)Nc1ccc2oc3c(OC(F)F)ccc(C(=O)Nc4c(Cl)cncc4Cl)c3c2c1
Molecular Formula
C20H13Cl2F2N3O5S
Molecular Weight
516.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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