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Buparlisib Hydrochloride

Product Specifications

CAS Number

1312445-63-8

Target

Apoptosis|||PI3K

Related Pathways

PI3K/Akt/mTOR signaling|||Apoptosis

Purity

0.9894

Bioactivity

Buparlisib Hydrochloride (BKM120 HCl) is a specific and orally bioavailable pan-class I PI3K inhibitor that competitively inhibits PI3K/AKT kinase at the nanomolar level and suppresses cancer cell growth, making it suitable for studying breast cancer, glioblastoma, and solid tumours.

Smiles

Cl.FC(F)(F)C1=CC(=NC=C1C=2N=C(N=C(C2)N3CCOCC3)N4CCOCC4)N

Molecular Formula

C18H22ClF3N6O2

Molecular Weight

446.85

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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