Buparlisib Hydrochloride
Product Specifications
CAS Number
1312445-63-8
Target
Apoptosis|||PI3K
Related Pathways
PI3K/Akt/mTOR signaling|||Apoptosis
Purity
0.9894
Bioactivity
Buparlisib Hydrochloride (BKM120 HCl) is a specific and orally bioavailable pan-class I PI3K inhibitor that competitively inhibits PI3K/AKT kinase at the nanomolar level and suppresses cancer cell growth, making it suitable for studying breast cancer, glioblastoma, and solid tumours.
Smiles
Cl.FC(F)(F)C1=CC(=NC=C1C=2N=C(N=C(C2)N3CCOCC3)N4CCOCC4)N
Molecular Formula
C18H22ClF3N6O2
Molecular Weight
446.85
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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