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NSC745885

Product Specifications

CAS Number

4219-52-7

Target

Histone Methyltransferase, Apoptosis

Related Pathways

Chromatin/Epigenetic, Apoptosis

Bioactivity

NSC745885 is an antitumor agent non-toxic to normal cells that downregulates EZH2 via proteasome-mediated degradation. It exhibits toxicity against multiple normal and drug-resistant cancer cell lines and may be used in studies of advanced bladder cancer and oral squamous cell carcinoma.

Smiles

O=C1C=2C=CC=CC2C(=O)C=3C4=NSN=C4C=CC13

Molecular Formula

C14H6N2O2S

Molecular Weight

266.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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