NSC745885
Product Specifications
CAS Number
4219-52-7
Target
Histone Methyltransferase|||Apoptosis
Related Pathways
Chromatin/Epigenetic|||Apoptosis
Bioactivity
NSC745885 is an antitumor agent non-toxic to normal cells that downregulates EZH2 via proteasome-mediated degradation. It exhibits toxicity against multiple normal and drug-resistant cancer cell lines and may be used in studies of advanced bladder cancer and oral squamous cell carcinoma.
Smiles
O=C1C=2C=CC=CC2C(=O)C=3C4=NSN=C4C=CC13
Molecular Formula
C14H6N2O2S
Molecular Weight
266.27
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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