Nitracrine
Product Specifications
CAS Number
4533-39-5
Target
Others, DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others
Bioactivity
Nitracrine is a 1-nitroacridine derivative and is an effective hypoxia-selective agent in vitro and antitumor drugs. Nitracrine suppresses RNA synthesis and covalently, reversibly binds to DNA but also forms covalent adducts with DNA in vivo. Nitracrine has cytotoxicity towards most cells.
Smiles
N(CCCN(C)C)C=1C2=C(N=C3C1C=CC=C3)C=CC=C2N(=O)=O
Molecular Formula
C18H20N4O2
Molecular Weight
324.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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