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NI-42

Product Specifications

CAS Number

1884640-99-6

Target

Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic

Purity

0.9918

Bioactivity

NI-42 is a structurally orthogonal chemical probe for the BRPFs and is biased. It effective inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM) . It also has excellent selectivity over nonclass IV BRD proteins.

Smiles

Cc1cc2cc(NS(=O)(=O)c3ccc(cc3)C#N)ccc2n(C)c1=O

Molecular Formula

C18H15N3O3S

Molecular Weight

353.39

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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