NI-42
Product Specifications
CAS Number
1884640-99-6
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Purity
0.9918
Bioactivity
NI-42 is a structurally orthogonal chemical probe for the BRPFs and is biased. It effective inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM) . It also has excellent selectivity over nonclass IV BRD proteins.
Smiles
Cc1cc2cc(NS(=O)(=O)c3ccc(cc3)C#N)ccc2n(C)c1=O
Molecular Formula
C18H15N3O3S
Molecular Weight
353.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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