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NFPS

Product Specifications

CAS Number

405225-21-0

Target

GlyT, Thrombin

Related Pathways

Neuroscience, Proteases/Proteasome

Bioactivity

NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion. NFPS is a selective and non-competitive glycine transporter-1 (GlyT1) inhibitor (IC50s: 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively) .

Smiles

C(OC1=CC=C(C=C1)C2=CC=CC=C2)(CCN(CC(O)=O)C)C3=CC=C(F)C=C3

Molecular Formula

C24H24FNO3

Molecular Weight

393.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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