NCT-502
Product Specifications
CAS Number
1542213-00-2
Target
Dehydrogenase
Related Pathways
Metabolism
Purity
0.996
Bioactivity
NCT-502 (N- (4,6-dimethylpyridin-2-yl) -4-[5- (trifluoromethyl) pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 μM against PHGDH.
Smiles
Cc1cc(C)nc(NC(=S)N2CCN(CC2)c2ccc(cn2)C(F)(F)F)c1
Molecular Formula
C18H20F3N5S
Molecular Weight
395.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
abx511056 96 Tests
Mouse Dual specificity protein phosphatase 13 isoform A (DUSP13) ELISA Kit
Sign In for Pricing
View Details 
20295-05021 150 µg
Human Heat Shock Protein 47 (HSP47) Antibody (Biotin Conjugate)
Sign In for Pricing
View Details MBS3805548-01 48 Well
Mouse Anti-Thyroid Microsome Antibody (ATMA/TMAB) ELISA Kit
Sign In for Pricing
View Details MBS3805548-02 96 Well
Mouse Anti-Thyroid Microsome Antibody (ATMA/TMAB) ELISA Kit
Sign In for Pricing
View Details MBS3805548-03 5x 96 Well
Mouse Anti-Thyroid Microsome Antibody (ATMA/TMAB) ELISA Kit
Sign In for Pricing
View Details MBS3805548-04 10x 96 Well
Mouse Anti-Thyroid Microsome Antibody (ATMA/TMAB) ELISA Kit
Sign In for Pricing
View Details