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NCT-502

Product Specifications

CAS Number

1542213-00-2

Target

Dehydrogenase

Related Pathways

Metabolism

Purity

0.996

Bioactivity

NCT-502 (N- (4,6-dimethylpyridin-2-yl) -4-[5- (trifluoromethyl) pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 μM against PHGDH.

Smiles

Cc1cc(C)nc(NC(=S)N2CCN(CC2)c2ccc(cn2)C(F)(F)F)c1

Molecular Formula

C18H20F3N5S

Molecular Weight

395.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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