Nanatinostat
Product Specifications
CAS Number
1256448-47-1
Target
Apoptosis, HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair, Apoptosis
Purity
0.9903
Bioactivity
Nanatinostat (CHR-3996) is an HDAC inhibitor with selectivity and oral bioavailability, with IC50 values of 3-7 nM for HDAC1/2/3 and >200 nM for other subtypes. Nanatinostat also inhibits tumour cell proliferation and induces apoptosis, for studying neurodegenerative diseases and cancer.
Smiles
N(CC1=NC2=C(C=C1)C=C(F)C=C2)[C@H]3[C@]4([C@@]3(CN(C4)C=5N=CC(C(NO)=O)=CN5)[H])[H]
Molecular Formula
C20H19FN6O2
Molecular Weight
394.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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