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Naluzotan

Product Specifications

CAS Number

740873-06-7

Target

EGFR, 5-HT Receptor, Potassium Channel

Related Pathways

Tyrosine Kinase/Adaptors, Neuroscience, JAK/STAT signaling, Membrane transporter/Ion channel, Angiogenesis, GPCR/G Protein

Purity

>99.99%

Bioactivity

Naluzotan (PRX 00023) is a novel and potent 5-HT1A agonist with IC50 and Ki values of approximately 20 nM and 5.1 nM, respectively.Naluzotan is a potent hERG K+ channel blocker with an IC50 value of 3800 nM.Naluzotan exhibits anxiolytic activity and can be used to study depression.

Smiles

CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1

Molecular Formula

C23H38N4O3S

Molecular Weight

450.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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