Naluzotan
Product Specifications
CAS Number
740873-06-7
Target
EGFR, 5-HT Receptor, Potassium Channel
Related Pathways
Tyrosine Kinase/Adaptors, Neuroscience, JAK/STAT signaling, Membrane transporter/Ion channel, Angiogenesis, GPCR/G Protein
Purity
>99.99%
Bioactivity
Naluzotan (PRX 00023) is a novel and potent 5-HT1A agonist with IC50 and Ki values of approximately 20 nM and 5.1 nM, respectively.Naluzotan is a potent hERG K+ channel blocker with an IC50 value of 3800 nM.Naluzotan exhibits anxiolytic activity and can be used to study depression.
Smiles
CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1
Molecular Formula
C23H38N4O3S
Molecular Weight
450.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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