Muramyl dipeptide
Product Specifications
CAS Number
53678-77-6
Target
P38 MAPK, NOD-like Receptor (NLR), NOD
Related Pathways
Immunology/Inflammation, MAPK, NF-κB
Purity
>99.99%
Bioactivity
Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. It indirectly decreases osteoclast differentiation by reducing the RANKL/OPG ratio and directly increases osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways, thereby inducing bone formation via Runx2.
Smiles
C[C@H](NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1NC(C)=O)C(=O)N[C@H](CCC(O)=O)C(N)=O
Molecular Formula
C19H32N4O11
Molecular Weight
492.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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