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MS417

Product Specifications

CAS Number

916489-36-6

Target

HIV Protease|||Epigenetic Reader Domain

Related Pathways

Microbiology/Virology|||Chromatin/Epigenetic|||Proteases/Proteasome

Purity

0.9988

Bioactivity

MS417 (GTPL7512) is an inhibitor of BET-specific BRD4 (BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weak selectivity at CBP BRD with IC50 of 32.7 ?M.

Smiles

COC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1

Molecular Formula

C20H19ClN4O2S

Molecular Weight

414.91

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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