MS4078
Product Specifications
CAS Number
2229036-62-6
Target
PROTACs, ALK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, PROTAC
Purity
0.9874
Bioactivity
MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19 nM for binding affinity to ALK.
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCNC(CN4CCC(CC4)C5=CC(OC(C)C)=C(NC=6N=C(NC7=C(S(C(C)C)(=O)=O)C=CC=C7)C(Cl)=CN6)C=C5C)=O
Molecular Formula
C45H52ClN9O8S
Molecular Weight
914.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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