MRT00033659
Product Specifications
CAS Number
1401731-54-1
Target
Others|||MDM-2/p53|||Chk|||Early 2 Factor (E2F) |||Casein Kinase
Related Pathways
Metabolism|||Cell Cycle/Checkpoint|||Apoptosis|||Stem Cells|||Others
Bioactivity
MRT00033659 is an effective broad-spectrum kinase inhibitor of CK1 (IC50=0.9 ?M for CK1?) and CHK1 (IC50=0.23 ?M) . MRT00033659 is a pyrazolo-pyridine analogue. It also induces p53 pathway activation and E2F-1 destabilization.
Smiles
CC(=O)Nc1cccc(c1)-c1cnc2[nH]nc(C)c2c1
Molecular Formula
C15H14N4O
Molecular Weight
266.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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