MRT00033659

Product Specifications

CAS Number

1401731-54-1

Target

Others|||MDM-2/p53|||Chk|||Early 2 Factor (E2F) |||Casein Kinase

Related Pathways

Metabolism|||Cell Cycle/Checkpoint|||Apoptosis|||Stem Cells|||Others

Bioactivity

MRT00033659 is an effective broad-spectrum kinase inhibitor of CK1 (IC50=0.9 ?M for CK1?) and CHK1 (IC50=0.23 ?M) . MRT00033659 is a pyrazolo-pyridine analogue. It also induces p53 pathway activation and E2F-1 destabilization.

Smiles

CC(=O)Nc1cccc(c1)-c1cnc2[nH]nc(C)c2c1

Molecular Formula

C15H14N4O

Molecular Weight

266.3

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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