MMV390048
Product Specifications
CAS Number
1314883-11-8
Target
Parasite, PI4K
Related Pathways
PI3K/Akt/mTOR signaling, Microbiology/Virology
Purity
0.9828
Bioactivity
MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM) . MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns.
Smiles
CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(c1)-c1ccc(nc1)C(F)(F)F
Molecular Formula
C18H14F3N3O2S
Molecular Weight
393.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
I7545-02A-ML550 100 µL
INDO, CT (Indoleamine 2,3-dioxygenase, IDO-1, EC 1.13.11.52, Indoleamine-pyrrole 2,3-dioxygenase, IDO1, INDO, IDO) (MaxLight 550) discontinued
Sign In for Pricing
View Details 
orb1663237-01 48 Tests
Human Toll Like Receptor Adaptor Molecule 1 (TICAM1) ELISA Kit
Sign In for Pricing
View Details orb1663237-02 96 Tests
Human Toll Like Receptor Adaptor Molecule 1 (TICAM1) ELISA Kit
Sign In for Pricing
View Details 
MBS2127623-01 0.1 mL
PE Linked Monoclonal Antibody to Chemokine (CXC Motif) Ligand 1 (CXCL1)
Sign In for Pricing
View Details MBS2127623-02 0.2 mL
PE Linked Monoclonal Antibody to Chemokine (CXC Motif) Ligand 1 (CXCL1)
Sign In for Pricing
View Details