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MMV390048

Product Specifications

CAS Number

1314883-11-8

Target

Parasite, PI4K

Related Pathways

PI3K/Akt/mTOR signaling, Microbiology/Virology

Purity

0.9828

Bioactivity

MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM) . MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns.

Smiles

CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(c1)-c1ccc(nc1)C(F)(F)F

Molecular Formula

C18H14F3N3O2S

Molecular Weight

393.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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