ML67-33
Product Specifications
CAS Number
1443290-89-8
Target
Potassium Channel, HIV Protease
Related Pathways
Proteases/Proteasome, Membrane transporter/Ion channel, Microbiology/Virology
Bioactivity
ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively) . ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels.
Smiles
CC1(C)c2cc(Cl)ccc2N(CCc2nnn[nH]2)c2ccc(Cl)cc12
Molecular Formula
C18H17Cl2N5
Molecular Weight
374.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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