ML-9
Product Specifications
CAS Number
105637-50-1
Target
Akt, Myosin, Calcium Channel
Related Pathways
Membrane transporter/Ion channel, Cytoskeletal Signaling, Metabolism, PI3K/Akt/mTOR signaling
Purity
0.9969
Bioactivity
ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 causes autophagy by stimulating autophagosome formation and inhibiting their degradation.
Smiles
Cl.Clc1cccc2c(cccc12)S(=O)(=O)N1CCCNCC1
Molecular Formula
C15H18Cl2N2O2S
Molecular Weight
361.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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