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Islatravir

Product Specifications

CAS Number

865363-93-5

Target

Reverse Transcriptase, HIV Protease

Related Pathways

Microbiology/Virology, Proteases/Proteasome

Purity

0.9877

Bioactivity

Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively) .

Smiles

Nc1nc(F)nc2n(cnc12)[C@H]1C[C@H](O)[C@@](CO)(O1)C#C

Molecular Formula

C12H12FN5O3

Molecular Weight

293.25

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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