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MK-0674

Product Specifications

CAS Number

887781-62-6

Target

Cysteine Protease

Related Pathways

Proteases/Proteasome

Purity

0.9991

Bioactivity

MK-0674 is an orally available, selective and potent cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S. It can be used in metabolism-related diseases.

Smiles

N(C([C@@H](N[C@H]([C@](F)(F)F)C1=CC=C(C=C1)C2=CC=C([C@H](C(F)F)O)C=C2)CC(C)(C)F)=O)C3(C#N)CC3

Molecular Formula

C26H27F6N3O2

Molecular Weight

527.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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