Quiflapon
Product Specifications
CAS Number
136668-42-3
Target
FLAP, Apoptosis
Related Pathways
Immunology/Inflammation, Apoptosis
Purity
0.9888
Bioactivity
Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotriene biosynthesis (LT) inhibitor (IC50: 3.1 and 6.1 nM in intact human and elicited rat PMNLs, respectively) .
Smiles
CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12
Molecular Formula
C34H35ClN2O3S
Molecular Weight
587.17
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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