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Quiflapon

Product Specifications

CAS Number

136668-42-3

Target

FLAP, Apoptosis

Related Pathways

Immunology/Inflammation, Apoptosis

Purity

0.9888

Bioactivity

Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotriene biosynthesis (LT) inhibitor (IC50: 3.1 and 6.1 nM in intact human and elicited rat PMNLs, respectively) .

Smiles

CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12

Molecular Formula

C34H35ClN2O3S

Molecular Weight

587.17

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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