Men 10376
Product Specifications
CAS Number
135306-85-3
Target
Neurokinin receptor, CDK
Related Pathways
GPCR/G Protein, Neuroscience, Cell Cycle/Checkpoint
Bioactivity
Men 10376 is a selective antagonist of tachykinin NK-2 receptor. It has a Ki of 4.4 μM for rat small intestine NK-2 receptor.
Smiles
C([C@H](C(N[C@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@@H](CCCCN)C(N)=O)=O)=O)NC([C@@H](NC([C@@H](CC=3C=4C(NC3)=CC=CC4)NC([C@H](CC5=CC=C(O)C=C5)NC([C@H](CC(O)=O)N)=O)=O)=O)C(C)C)=O)C=6C=7C(NC6)=CC=CC7
Molecular Formula
C57H68N12O10
Molecular Weight
1081.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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