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MC-GGFG-DX8951

Product Specifications

CAS Number

1600418-29-8

Target

Drug-Linker Conjugates for ADC, Topoisomerase

Related Pathways

Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair

Purity

0.9904

Bioactivity

MC-GGFG-DX8951 (MC-GGFG-Exatecan) is an antibody-coupled drug (ADC) drug-linker conjugate (DLC) consisting of DX8951, a potent DNA topoisomerase I inhibitor, the linker MC, and the cleavable peptide chain GGFG, and has antitumor potential.

Smiles

N(C(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCCCN2C(=O)C=CC2=O)=O)=O)=O)=O)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8

Molecular Formula

C49H51FN8O11

Molecular Weight

946.98

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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