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LY2922470

Product Specifications

CAS Number

1423018-12-5

Target

GPCR

Related Pathways

Endocrinology/Hormones, GPCR/G Protein

Purity

0.9708

Bioactivity

LY2922470 is a potent, selective G protein-coupled receptor 40 (GPR40) agonist, with EC50s of 7 nM for human GPR40, 1 nM for mouse GPR40 and 3 nM for rat GPR40, respectively. LY2922470 reduces glucose levels along and increases insulin and GLP-1 significantly.

Smiles

COc1cccc2CCCN(Cc3ccc(COc4ccc(cc4)[C@H](CC(O)=O)C#CC)s3)c12

Molecular Formula

C28H29NO4S

Molecular Weight

475.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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