Merestinib dihydrochloride

Product Specifications

CAS Number

1206801-37-7

Target

Discoidin Domain Receptor (DDR) |||c-Met/HGFR|||ROS Kinase|||FLT|||TAM Receptor|||Tyrosine Kinases

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors

Bioactivity

Merestinib dihydrochloride (LY2801653 dihydrochloride) is an orally available kinase inhibitor with antitumor activity that inhibits MET, AXL, RON, and MKNK1/2, and inhibits the growth of NTRK fusion-carrying tumors.

Smiles

Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1.Cl.Cl

Molecular Formula

C30H24Cl2F2N6O3

Molecular Weight

625.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

FAB20871JF669 0.1 mL

Mouse Monoclonal FCRL5/FCRL3 Antibody (307307) [Janelia Fluor 669]

Ask

View Details

abx940904-01 15 nmol

Human ZNF573 siRNA

Ask

View Details

abx940904-02 30 nmol

Human ZNF573 siRNA

Ask

View Details

539655-01 30ul

NFkappaB-p105/p50 discontinued

Ask

View Details

539655-02 100 µL

NFkappaB-p105/p50 discontinued

Ask

View Details

OR1042626-01 100 mg

(R) -2-[ (tert-Butoxycarbonyl) amino]-2-methyl-3-phenylpropionic acid

Ask

View Details