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Merestinib dihydrochloride

Product Specifications

CAS Number

1206801-37-7

Target

Discoidin Domain Receptor (DDR) |||c-Met/HGFR|||ROS Kinase|||FLT|||TAM Receptor|||Tyrosine Kinases

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors

Bioactivity

Merestinib dihydrochloride (LY2801653 dihydrochloride) is an orally available kinase inhibitor with antitumor activity that inhibits MET, AXL, RON, and MKNK1/2, and inhibits the growth of NTRK fusion-carrying tumors.

Smiles

Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1.Cl.Cl

Molecular Formula

C30H24Cl2F2N6O3

Molecular Weight

625.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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