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Luzindole

Product Specifications

CAS Number

117946-91-5

Target

MT Receptor, Melatonin Receptor

Related Pathways

Neuroscience, GPCR/G Protein

Purity

0.9896

Bioactivity

Luzindole (N-0774) is a selective melatonin receptor antagonist that inhibits experimental autoimmune encephalomyelitis and exhibits antidepressant-like activity. It preferentially targets MT2 (Mel1b) over MT1 (Mel1a), with Ki values of 10.2 nM for human MT2 and 158 nM for MT1.

Smiles

CC(=O)NCCc1c(Cc2ccccc2)[nH]c2ccccc12

Molecular Formula

C19H20N2O

Molecular Weight

292.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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