Luzindole
Product Specifications
CAS Number
117946-91-5
Target
MT Receptor, Melatonin Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Purity
0.9896
Bioactivity
Luzindole (N-0774) is a selective melatonin receptor antagonist that inhibits experimental autoimmune encephalomyelitis and exhibits antidepressant-like activity. It preferentially targets MT2 (Mel1b) over MT1 (Mel1a), with Ki values of 10.2 nM for human MT2 and 158 nM for MT1.
Smiles
CC(=O)NCCc1c(Cc2ccccc2)[nH]c2ccccc12
Molecular Formula
C19H20N2O
Molecular Weight
292.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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