LLY-283
Product Specifications
CAS Number
2040291-27-6
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.9949
Bioactivity
LLY-283 is a potent, selective, and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, exhibiting an IC50 of 22 nM and a Kd of 6 nM for the PRMT5:MEP50 complex, and demonstrates antitumor activity.
Smiles
[H][C@@]1(O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(N)ncnc12)[C@H](O)c1ccccc1
Molecular Formula
C17H18N4O4
Molecular Weight
342.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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