Lexibulin dihydrochloride
Product Specifications
CAS Number
917111-49-0
Target
Apoptosis, Reactive Oxygen Species, Others, ROS, Microtubule Associated
Related Pathways
Apoptosis, Metabolism, Immunology/Inflammation, Others, NF-κB, Cytoskeletal Signaling
Bioactivity
Lexibulin 2Hcl is an effective tubulin polymerization inhibitor (IC50: 10-100 nM in cancer cell lines) . It also has potent cytotoxic and vascular disrupting activity in vitro and in vivo.
Smiles
COC1=C(NC(NCC)=O)C=CC(C2=NC=C(C)C(N[C@H](C3=CN=CC=C3)CCC)=N2)=C1.Cl.Cl
Molecular Formula
C24H32Cl2N6O2
Molecular Weight
507.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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