Leriglitazone
Product Specifications
CAS Number
146062-44-4
Target
Others|||PPAR
Related Pathways
DNA Damage/DNA Repair|||Metabolism|||Others
Bioactivity
Leriglitazone, a metabolite of pioglitazone, binds to the PPAR? C-terminal ligand-binding domain (Ki: 1.2 ?M) and induces transcriptional efficacy of the PPAR? (EC50: 680 nM) . Leriglitazone PioOH is a PPAR? agonist, stabilizes the PPAR? activation function-2 (AF-2) co-activator binding surface.
Smiles
O=C1SC(C(=O)N1)CC2=CC=C(OCCC3=NC=C(C=C3)C(O)C)C=C2
Molecular Formula
C19H20N2O4S
Molecular Weight
372.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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