Leriglitazone
Product Specifications
CAS Number
146062-44-4
Target
Others, PPAR
Related Pathways
DNA Damage/DNA Repair, Metabolism, Others
Bioactivity
Leriglitazone, a metabolite of pioglitazone, binds to the PPARγ C-terminal ligand-binding domain (Ki: 1.2 μM) and induces transcriptional efficacy of the PPARγ (EC50: 680 nM) . Leriglitazone PioOH is a PPARγ agonist, stabilizes the PPARγ activation function-2 (AF-2) co-activator binding surface.
Smiles
O=C1SC(C(=O)N1)CC2=CC=C(OCCC3=NC=C(C=C3)C(O)C)C=C2
Molecular Formula
C19H20N2O4S
Molecular Weight
372.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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