Ribociclib succinate
Product Specifications
CAS Number
1374639-75-4
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.999
Bioactivity
Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and exhibits over 1,000-fold reduced potency against the cyclin B/CDK1 complex.
Smiles
OC(=O)CCC(O)=O.CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1
Molecular Formula
C27H36N8O5
Molecular Weight
552.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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