Ribociclib succinate

Product Specifications

CAS Number

1374639-75-4

Target

CDK

Related Pathways

Cell Cycle/Checkpoint

Purity

0.999

Bioactivity

Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and exhibits over 1,000-fold reduced potency against the cyclin B/CDK1 complex.

Smiles

OC(=O)CCC(O)=O.CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1

Molecular Formula

C27H36N8O5

Molecular Weight

552.63

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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