LBW242
Product Specifications
CAS Number
867324-12-7
Target
Others, FLT, IAP
Related Pathways
Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors, Others
Bioactivity
LBW242 is a 3-mer and Smac mimetic and is an effective and orally active proapoptotic IAP inhibitor. LBW242 has activity against multiple myeloma and potentiates TRAIL- and anticancer drug-mediated cell death of ovarian cancer cells. LBW242 displays effects on mutant FLT3-expressing cells.
Smiles
C([C@@H](NC([C@@H](NC)C)=O)[C@H]1CCCCC1)(=O)N2[C@]3([C@@](CC2)(CCN(CCC4=CC=CC=C4)C3)[H])[H]
Molecular Formula
C27H42N4O2
Molecular Weight
454.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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