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Larotaxel

Product Specifications

CAS Number

156294-36-9

Target

P-gp, Apoptosis

Related Pathways

Apoptosis, Membrane transporter/Ion channel, Neuroscience

Purity

0.9922

Bioactivity

Larotaxel (XRP9881) is a taxane analogue with anticancer activity that promotes tubulin assembly and stabilizes microtubules, inducing apoptosis. It crosses the blood-brain barrier and has a higher affinity for Docetaxel than P-glycoprotein 1, making it useful for studying breast and bladder cancer.

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[H][C@@]12C[C@@H]3C[C@@]33C(=O)[C@]([H])(OC(C)=O)C4=C(C)[C@@H](C[C@@](O)([C@@H](OC(=O)c5ccccc5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1

Molecular Formula

C45H53NO14

Molecular Weight

831.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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