Larotaxel
Product Specifications
CAS Number
156294-36-9
Target
P-gp|||Apoptosis
Related Pathways
Apoptosis|||Membrane transporter/Ion channel|||Neuroscience
Purity
0.9922
Bioactivity
Larotaxel (XRP9881) is a taxane analogue with anticancer activity that promotes tubulin assembly and stabilizes microtubules, inducing apoptosis. It crosses the blood-brain barrier and has a higher affinity for Docetaxel than P-glycoprotein 1, making it useful for studying breast and bladder cancer.
Smiles
[H][C@@]12C[C@@H]3C[C@@]33C(=O)[C@]([H])(OC(C)=O)C4=C(C)[C@@H](C[C@@](O)([C@@H](OC(=O)c5ccccc5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1
Molecular Formula
C45H53NO14
Molecular Weight
831.9
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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