L-161982
Product Specifications
CAS Number
147776-06-5
Target
Prostaglandin Receptor
Related Pathways
Immunology/Inflammation, GPCR/G Protein
Purity
0.9991
Bioactivity
L-161982 is a selective EP4 receptor antagonist that inhibits PGE2-induced ERK phosphorylation and cell proliferation in HCA-7 cells and alleviates collagen-induced arthritis in mice.
Smiles
O=C1N(N=C(CCCC)N1CC2=CC=C(C=C2)C3=C(S(NC(=O)C4=C(C)C=CS4)(=O)=O)C=CC=C3)C5=C(C(F)(F)F)C=CC=C5
Molecular Formula
C32H29F3N4O4S2
Molecular Weight
654.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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