KIN1408
Product Specifications
CAS Number
1903800-11-2
Target
Anti-infection, Antiviral, HCV Protease
Related Pathways
Proteases/Proteasome, Microbiology/Virology, Immunology/Inflammation
Purity
0.9861
Bioactivity
KIN1408 is an antiviral small molecule compound that is an agonist of the RIG-1-like receptor (RLR) pathway and is able to drive the activation of IRF3 (Interferon Regulatory Factor 3) to induce the expression of innate immunity genes (e.g., MDA5, RIG-1, Mx1, IRF7, and IFIT1), and to promote the nuclear translocation of IRF3 by targeting MAVS (Mitochondrial Antiviral Signaling Protein) or its upstream IRF3 nuclear translocation by targeting MAVS (mitochondrial antiviral signaling protein) or its upstream factors. KIN1400 is the parent, and KIN1409 is a derivative.
Smiles
COc1ccc2sc(NC(c3ccc(OC(F)F)cc3)c3ccc4cccnc4c3O)nc2c1
Molecular Formula
C25H19F2N3O3S
Molecular Weight
479.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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